微生物与生化药学——微生物学方向

张玉琴

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时间:2021-07-02    

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张玉琴   微生物菌种保藏研究室   研究员   博士生导师

教育背景及工作经历:

2015/07-至今 中国医学科学院医药生物技术研究所 研究员

2014/04-2015/06  中国医学科学院医药生物技术研究所 副研究员

2013/04-2014/03  美国科特州立大学生命科学系 访问学者

2009/05-2013/03  中国医学科学院医药生物技术研究所 副研究员

2009/01- 2009/04  韩国生命科学和生物技术研究所 访问学者

2005/08-2009/01  中国医学科学院医药生物技术研究所 助理研究员

2005/09-2008/06  云南大学 微生物学专业 博士研究生

2003/09-2005/06 云南大学 微生物学专业 硕士研究生

1991/09-1995/06  西南大学 生物学教育专业 大学本科

主要研究方向:微生物新资源以及微生物与环境的相互关系

专业研究领域:药用微生物资源及其应用;微生物系统学、微生物生态学和基因组学

代表性论文:

1. Ye Sun, Hao Wang, Tao Zhang, Wei-Hong Liu, Li-Yan Yu, Yu-Qin Zhang*. Desertihabitans aurantiacus gen. nov., sp. nov., a novel member of the family Propionibacteriaceae. Int J Syst Evol Microbiol 2019; 69(8):2486-2491. doi: 10.1099/ijsem.0.003519.

2. Ye Sun, Wei-Hong Liu, Meng-Jie Ai, Jing Su, Li-Yan Yu, Yu-Qin Zhang*. Aeromicrobium lacus sp. nov., a novel actinobacterium isolated from a drinking-water reservoir. Int J Syst Evol Microbiol 2019; 69(2): 460-464. doi: 10.1099/ijsem.0.003181.

3. Yun-Lei Shi, Ye Sun, Zhu-Ming Jiang, Zhi-Yong Ruan, Jing Su, Li-Yan Yu, Yu-Qin Zhang*. Simplicispira lacusdiani sp. nov., a novel betaproteobacterium isolated from a freshwater reservoir. Int J Syst Evol Microbiol 2019; 69(1): 129-133. doi: 10.1099/ijsem.0.003112.

4. Ye Sun, Zhu-Ming Jiang, Li-Li Zhao, Jing Su, Li-Yan Yu, Yong-Qiang Tian, Yu-Qin Zhang*. Allorhizocola rhizosphaerae gen. nov., sp. nov., a new member of Micromonosporaceae isolated from rhizosphere soil of the plant Calligonum mongolicum. Int J Syst Evol Microbiol 2019; 69(1): 109-115. doi: 10.1099/ijsem.0.003114.

5. Anjali Krishnan, Yu-Qin Zhang, Xiaozhen Mou. Isolation and characterization of microcystin-degrading bacteria from lake Erie. Environmental Contamination and Toxicology 2018; 101(5): 617-623. doi: 10.1007/s00128-018-2468-4

6. Ye Sun, Yun-Lei Shi, Hao Wang, Tao Zhang, Li-Yan Yu, Henry Sun, Yu-Qin Zhang*. Diversity of bacteria and the characteristics of actinobacteria community structure in Badain Jaran Desert and Tengger Desert of China. Front Microbiol 2018; 9:1068. doi: 10.3389/fmicb.2018.01068.

7. Yong Li, Meng-Jie Ai, Ye Sun, Yu-Qin Zhang*, Jian-Qiang Zhang. Spirosoma lacussanchae sp. nov., a phosphate-solubilizing bacterium isolated from a fresh water reservoir. Int J Syst  Evol Microbiol, 2017, 67: 3144–3149.

8. Meng-Jie Ai, Ye Sun, Hong-Min Sun, Hong-Yu Liu, Li-Yan Yu, Yu-Qin Zhang*. Allobranchiibius huperziae gen. nov., sp. nov., a member of Dermacoccaceae isolated from the root of a medicinal plant Huperzia serrata (Thunb.) Int J Syst Evol Microbiol. 2017, 67: 4210-4215.

9. Ye Sun, Hua-Hong Chen, Sun, Hong-Min Sun,  Meng-Jie Ai, Jing Su, Li-Yan Yu, Yu-Qin Zhang*. Naumannella huperziaus sp. nov., a novel endophytic actinobacterium isolated from Huperzae serrata (Thunb.). Int J Syst Evol Microbiol. 2017, 67: 1867–1872.

10. Xiao-mei Fang, Jing Su, Hao Wang, Tao Zhang, Li-li Zhao, Hong-yu Liu, Bai-ping Ma, Yu-qin Zhang, Li-yan Yu. Paenibacillus eucommiae sp. nov., isolated from a  traditional Chinese medicinal herbal plant Eucommia ulmoides Oliver. Int J Syst Evol  Microbiol. 2017, 67: 993-997.

11. Chang-feng Zhang, Meng-Jie Ai, Ju-Xian Wang, Shao-Wei Liu, Li-Li Zhao, Jing Su, Li-Yan Yu, Yu-Qin Zhang*. Herbihabitans rhizosphaerae gen. nov. sp. nov., a member of Pseudonocardiaceae isolated from the rhizosphere soil of the herb Limonium sinense (Girard). Int J Syst Evol Microbiol, 2016, 66(11): 4156-4161.

12. Zhi-Lian Gong, Meng-Jie Ai, Hong-Min Sun, Hong-Yu Liu, Li-Yan Yu, Yu-Qin Zhang*. Jatrophihabitans huperziaus sp. nov.a novel endophytic actinobacterium isolated from the surface-sterilized medicinal plant Huperzia serrata (Thunb.). Int J Syst Evol Microbiol, 2016, 66(11): 3972-3977.

13. Chang-feng Zhang, Meng-Jie Ai, Li-Li Zhao, Hong-Yu Liu, Li-Yan Yu, Yu-Qin Zhang*. Microlunatus nigridraconis sp. nov. a novel actinobacterial member from rhizosphere soil. Int J Syst Evol Microbiol, 2016, 66 (9): 3614-3618.

14. Zhi-Lian Gong, Chang-Feng Zhang, Rong Jin, Yu-Qin Zhang*. Steroidobacter flavus sp. nov., a microcystin-degrading Gammaproteobacterium isolated from soil. Antonie van Leeuwenhoek 2016. 109(8): 1073-1079.

15. Hongmin Sun, Yuzhen Wei, Xiaomei Fang, Liyan Yu, Yu-Qin Zhang*. Diversity of endophytic bacteria isolated from Huperzia serrata. Acta Microbiologica Sinica. 2016, 56(4): 614-628.

16. Bing-Huo Zhang, Zhang-Gui Ding, Han-Quan Li, Xiao-Zhen Mou, Yu-Qin Zhang, Jian-Yuan Yang, En-Min Zhou, Wen-Jun Li. Algicidal Activity of Streptomyces eurocidicus JXJ-0089 Metabolites and Their Effects on Microcystis Physiology. Applied and Environmental Microbiology, 2016.

17. Dong Yan, Tao Zhang, Jing Su J, Li-Li Zhao, Hao Wang, Xiao-Mei Fang X-M, Yu-Qin Zhang, Hong-Yu Liu, Li-Yan Yu. Diversity and Composition of Airborne Fungal Community Associated with Particulate Matters in Beijing during Haze and Non-haze Days. Front. Microbiol. 7:487. doi: 10.3389/fmicb. 2016.00487

18.Hongmin Sun, Liyan Yu, Yu-Qin Zhang*. Recent advance in Geodermatophilaceae. Acta Microbiologica Sinica. 2015, 55(12): 1521-1529.

19. Hong-Min Sun, Tao Zhang, Li-Yan Yu, Yu-Qin Zhang*. Ubiquity, Diversity and Physiological Characteristics of Geodermatophilaceae in Shapotou National Desert Ecological Reserve. Front. Microbiol. 6:1059. doi:10.3389/fmicb.2015.01059

20. Hong-Min Sun, Tao Zhang, Li-Yan Yu, Xin-Xin Lu, Xiao-Zhen Mou, Yu-Qin Zhang*. Tenggerimyces mesophilus gen. nov., sp. nov., a novel member of the family Nocardioidaceae. Int J Syst Evol Microbiol, 2015, 65(10): 3359-3364.

专利:

1. 寡养单胞菌属新物种及其应用的制作方法. 申请号:202010150659.0.申请人:张玉琴;牛秋红;邓阳;魏旭阳;刘红宇;余利岩。申请日期:2020.3.6

2. 申氏杆菌属新物种及其应用。专利号:ZL 2019 1 0613434.1。申请人:张玉琴;邓阳;姜竹鸣;孙烨;王浩;张涛;苏静;余利岩。申请日期:2019.7.9。授权日期:2021.3.16.

3. 贫养杆菌属新物种及其应用。专利号:ZL 2019 1 061338.5 申请人:张玉琴;姜竹鸣;王浩;张涛;石云雷;邓阳;刘红宇;余利岩。申请日期:2019.7.9。授权日期:2021.3.12.

4. 两株游动放线菌及其在抗细菌中的应用。申请号:2011101750995。申请人:余利岩, 张月琴, 董国霞, 李子强, 孙薇, 张玉琴, 李秋萍, 魏玉珍.申请日期:2011.6.27;授权日期:2015.10.7

5. 一种产生抗HIV活性物质的链霉菌及其应用。申请号 : CN201510221567.6。申请人:余利岩,庞旭,岑山,马铃,方晓梅,魏玉珍,李晓宇,刘红宇,张玉琴。申请日期:2015.5.4

6. 一种4-羟基苯丙烯酸衍生物、其制备方法及其应用。专利申请号:201110153640.2。申请人:余利岩, 黄彬, 王玉成, 许乐幸, 游雪甫, 刘红宇, 张玉琴, 司书毅。申请日期:2011.6.9

专著:

1.《放线菌系统学:原理、方法及实践》-第四、五、六章. 北京:科学出版社,2007.

2.《放线菌系统分类技术》-第四章. 北京:化学工业出版社,2015.

荣誉奖励:2009年获得云南省科学技术一等奖(排名第二)

学术任职:Frontiers in microbiology杂志客座编辑

联系电话:010- 83167110

电子邮箱:yzhang@imb.pumc.edu.cn